The Cryogen-free Measurement System. CryoAdvance, Inc.

Liquid nitrogen freezer BioCryo102 is designed for microprocessor controlled cooling/heating of biologic samples in the temperature interval -190 ... +50 °C. The freezing rates are programmable in the interval from 0.1 to 7 degrees/min. The biologic samples for cooling/ thawing are placed in the sample chamber which is connected to the inner or outer liquid nitrogen reservoir. The liquid nitrogen flow rate is regulated by a heater placed inside of reservoir. Liquid nitrogen evaporates and flows into the active chamber to cool the samples. The sample chamber shape in various modifications corresponds to the type of samples (vials, straws, pockets). The active chamber and inner reservoir are temperature isolated using vacuum isolation. This results in low external heat flows and low liquid nitrogen consumption. The freezing/heating protocols are controlled by microprocessor according to the user defined way. The user can set basic points of the protocol in the interval -190 ... +50 °C and cooling/heating rates between them. The number of basic points can be varied between 2 and 7.

The structure of the driving program enables linear protocols and approximation of nonlinear. The used-optimized protocol can be stored in the device memory. The microprocessor contains 10 standard protocols for different biologic samples. The control device is equipped by light and sound alarm which indicates the status of biologic samples. The samples can be held at a constant temperature for a long time.

Temperature interval, °С

- 190 ... + 50

Cooling rates, °C/min

0.1 ... 7

Accuracy of temperature stabilization, °C

0.05 ... 1

Accuracy of temperature indication, °C

0.2

Type of cryogenic liquid

Liquid nitrogen

Inner reservoir volume, L

2

Maximum number of the test tubes

21

Computer interface

RS-232

Program type

Variable with 2 ... 7 temperature set points and temperature variation rates, acoustic alarm at set points, system state monitoring

Protocol type

Linear/Nonlinear

Working time at -190 °С using inner reservoir, hours

> 10

Power supply, V

~ 220

Weight, kg

12

Dimensions, mm

800 х 400 х 150